Product Description

L3MBTL3 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS8814-50, BS8814-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q96JM7

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IF, IP,

All Applications: WB 1:500 - 1:2000
IF 1:50 - 1:100
IP 1:50 - 1:200

Background: L3MBTL3 (lethal(3)malignant brain tumor-like protein 3), also known as MBT-1 or KIAA1798, is a 780 amino acid protein containing three MBT repeats and one SAM (sterile alpha motif) domain. Localized to the nucleus, L3MBTL3 interacts with RING1B, another PcG protein that may be involved in the specification of anterior-posterior axis and cell proliferation in early development. L3MBTL3 exists as two isoforms produced by alternative splicing events.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: L3MBTL3 polyclonal antibody detects endogenous levels of L3MBTL3 protein.

Bioworld Molecular Weight: ~ 110 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using L3MBTL3 antibody at 1:1000 dilution., Immunofluorescence analysis of MCF7 cell using L3MBTL3 antibody. Blue: DAPI for nuclear staining., Immunoprecipitation analysis of 200ug extracts of HeLa cells using 1ug L3MBTL3 antibody. Western blot was performed from the immunoprecipitate using L3MBTL3 antibody at a dilition of 1:1000.

Alternative Name: Lethal(3)malignant brain tumor-like protein 3; H-l(3)mbt-like protein 3; L(3)mbt-like protein 3; MBT-1; L3MBTL3; KIAA1798, MBT1

Immunogen: Recombinant full length Human L3MBTL3.

Conjugate: Unconjugated

Modification: Unmodified