Product Description

Lactoferrin Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65924-50, BS65924-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P02788

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P

All Applications: WB 1:500 - 1:2000
IHC-P 1:100 - 1:200

Background: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Lactoferrin Polyclonal Antibody detects endogenous levels of Lactoferrin protein.

Bioworld Molecular Weight: ~ 85 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Rat lung, using LTF pAb at 1:1500 dilution., Immunohistochemistry analysis of paraffin-embedded rat kidney using LTF antibody at dilution of 1:100 (40x lens)., Immunohistochemistry analysis of paraffin-embedded human placenta using LTF antibody at dilution of 1:100 (40x lens)., Immunohistochemistry analysis of paraffin-embedded mouse kidney using LTF antibody at dilution of 1:100 (40x lens).

Alternative Name: CKRX; GIG12; Growth inhibiting protein 12; HLF2; Homo sapiens chemokine receptor X; Kaliocin 1; Lactoferrin; Lactoferroxin A; Lactoferroxin B; Lactoferroxin C; Lactoferroxin-C; Lactotransferrin; LF; LTF; Neutrophil lactoferrin; Talalactoferrin alfa; Talalactoferrin; TRFL_HUMAN

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-352 of human LTF (NP_002334.2).

Conjugate: Unconjugated

Modification: Unmodified