Product Description

Lambda light chain Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66706-50, MB66706-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: V region of the variable domain of immunoglobμlin light chains that participates in the antigen recognition. Immunoglobμlins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobμlins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobμlins-secreting plasma cells. Secreted immunoglobμlins mediate the effector phase of humoral immunity, which resμlts in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobμlin has two antigen binding sites with remarkable affinity for a particμlar antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particμlar antigen.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB, IHC

Alternate Names: Immunoglobμlin lambda variable 1-51, Ig lambda chain V-I region BL2, Ig lambda chain V-I region EPS, Ig lambda chain V-I region NEW, Ig lambda chain V-I region NIG-64

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: This antibody is generated from mouse immunized with Lambda light chain recombinant protein.

Dilution: WB (1/500 - 1/1000), IHC (1/20 - 1/50)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of Lambda light chain protein.

Molecular Weight: ~ 28 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P01701

Product: Mouse IgG2a kappa. Liquid in PBS, and 0.01% sodium azide.

Research Use Only