Product Description

Lamin A/C Mouse Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA11596-50, RA11596-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: lamin A/C (LMNA) Homo sapiens The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012],

Reactivity: Human

Host: Mouse

Applications: WB, IF/ICC

Alternate Names: 70 kDa lamin, Cardiomyopathy dilated 1A (autosomal dominant), CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LAMIN A, lamin A/C, Lamin A/C like 1, Lamin, LAMIN C, Lamin-A/C, LDP1, LFP, LGMD1B, Limb girdle muscular dystrophy 1B (autosomal dominant), LMN 1, LMN A, LMN C, LMN1, LMNA, LMNA_HUMAN, LMNC, LMNL1, Prelamin A/C, PRO1, Renal carcinoma antigen NY REN 32, Renal carcinoma antigen NY-REN-32, Renal carcinoma antigen NYREN32.

Clonality: Monoclonal

Dilution: wb dilution 1:1000 icc dilution 1:200

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 4000

Protein Molecular Weight（KDa): 74/63

Molecular Weight: 74/63

Research Use Only