Product Description

Lamin A/C (R386) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1446-50, BS1446-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellμlar longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellμlar morphology.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: Prelamin-A/C, Lamin-A/C, Lamin A/C, LaminA/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1, Lamin A, LaminA, Lamin-A, Lamin C, LaminC, Lamin-C

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 351-400 of Human Lamin A/C.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Lamin A/C (R386) polyclonal antibody detects endogenous levels of Lamin A/C protein.

Molecular Weight: ~ 74, 65 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P02545

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only