Lamin B Receptor Polyclonal Antibody-BS65905

Lamin B Receptor Polyclonal Antibody

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BS65905-50, BS65905-100

Swiss-Prot: Q14739

Host: Rabbit

Lamin B Receptor Polyclonal Antibody-BS65905

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit,

Applications: WB,

All Applications: WB=1:500-2000

Background: Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.

Purification and Purity: affinity purified by Protein A

Specificity: Lamin B Receptor Polyclonal Antibody detects endogenous levels of Lamin B Receptor protein.

Bioworld Molecular Weight: 68 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary: Anti-Lamin B Receptor at 1/1000 dilution, Primary: Anti-Lamin B Receptor at 1/1000 dilution

Alternative Name: LBR_HUMAN; LMN2R; PHA; DHCR 14B; DHCR14B antibody Integral nuclear envelope inner membrane protein; Lamin-B receptor; LBR; LMN 2R; LMN2R; MGC9041; PHA; PRO0650; DHCR14B; MGC9041.

Immunogen: KLH conjugated synthetic peptide derived from human Lamin B Receptor:1-100/615

Modification: Unmodified

Conjugate: Unconjugated