Product Description

Lamin B Receptor Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65905-50, BS65905-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Lamins are nuclear membrane proteins that serve to maintain specific cellμlar functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins resμlts in nuclear disregμlation and cell death.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit

Host: Rabbit

Applications: WB

Alternate Names: LBR_HUMAN, LMN2R, PHA, DHCR 14B, DHCR14B antibody Integral nuclear envelope inner membrane protein, Lamin-B receptor, LBR, LMN 2R, LMN2R, MGC9041, PHA, PRO0650, DHCR14B, MGC9041.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human Lamin B Receptor:1-100/615

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: Lamin B Receptor Polyclonal Antibody detects endogenous levels of Lamin B Receptor protein.

Molecular Weight: 68 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q14739

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only