Product Description

Laminin 2 alpha Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS65433-50, BS65433-100

Sizes: 50µl, 100µl

Swiss-Prot: P24043

Host: Rabbit

Reactivity: Human, Mouse

Applications: IF IHC

Background: Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Laminin 2 alpha Polyclonal Antibody detects endogenous levels of Laminin 2 alpha protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunofluorescence analysis of NIH3T3 cells using Laminin 2 alpha antibody at dilution of 1:50., Immunohistochemistry of paraffin-embedded Human Placenta using Laminin 2 alpha antibody at dilution of 1:50.

Bioworld Molecular Weight: ~ 343 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: LAMA 2; LAMA2; LAMA2; LAMA2_HUMAN; Laminin alpha 2 (merosin congenital muscular dystrophy); Laminin alpha 2; Laminin alpha 2 chain; Laminin alpha 2 subunit; Laminin M; Laminin M chain; Laminin subunit alpha-2; Laminin-12 subunit alpha; Laminin-2 subunit alpha; Laminin-4 subunit alpha; LAMM; LAMM; Merosin heavy chain; Merosin heavy chain; Laminin-12 subunit alpha

Immunogen: Synthetic peptide, corresponding to Human Laminin 2 alpha.

Conjugate: Unconjugated

Modification: Unmodified