Laminin alpha 5 Polyclonal Antibody-BZ16445

Laminin alpha 5 Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16445-50, BZ16445-100

Swiss-Prot: O15230

Host: Rabbit

Laminin alpha 5 Polyclonal Antibody-BZ16445

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse

Applications: WB, IHC-P, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background: Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 400 kDa; Observed MW: 400 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Laminin alpha 5 in RAW, HepG2, A549Lysates using Laminin alpha 5 antibody., Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue, using LAMA5 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample withBlocking peptide on the right.

Alternative Name: Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha

Immunogen: The antiserum was produced against synthesized peptide derived from human LAMA5. AA range:2381-2430

Modification: Unmodified

Conjugate: Unconjugated