Product Description

Laminin-R (Q215) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3689-50, BS3689-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Laminin receptor (Laminin-R) has a heterodimeric structure similar to that of receptors for other extracellμlar matrix proteins such as Fibronectin and Vitronectin. Incorporation of Laminin-R into lysosomal membranes makes it possible for lysosomes to attach to surfaces coated with Laminin. This and other properties identify Laminin-R as a member of the integrin family of cell adhesion receptors. The Laminin-R precursor is a polypeptide whose expression is consistently upregμlated in aggressive carcinoma. Laminin-R (also known as colon carcinoma laminin-binding protein) and is found at nine-fold higher levels in colon carcinoma than in adjacent normal colonic epithelium. Additionally, the level of the Laminin-R is higher in the lung cancer cell line than in the lung cell line.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: 40S ribosomal protein SA, 37 kDa laminin receptor precursor, 37LRP, 37/67 kDa laminin receptor, LRP/LR, 67 kDa laminin receptor, 67LR, Colon carcinoma laminin-binding protein, Laminin receptor 1, LamR, Laminin-binding protein precursor p40, LBP/p40, Mμltidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, LAMBR, LAMR1, RPSA

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 181-230 of Human Laminin-R.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Laminin-R (Q215) polyclonal antibody detects endogenous levels of Laminin-R protein.

Molecular Weight: ~ 40 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P08865

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only