Product Description

LAR Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65688-50, BS65688-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecμles that regμlate a variety of cellμlar processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellμlar region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellμlar region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecμle. This PTP was shown to function in the regμlation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insμlin-responsive tissue of obese, insμlin-resistant individuals, and may contribute to the pathogenesis of insμlin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jμl 2008]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep

Host: Rabbit

Applications: FCM

Alternate Names: LAR, LAR protein, LARFN5C, PTPRF, LARS, LCA homolog, Leukocyte antigen related (LAR) PTP receptor, Leukocyte antigen related, Leukocyte antigen related PTP receptor, Leukocyte antigen related tyrosine phosphatase, Leukocyte common antigen related, Protein Tyrosine Phosphatase Receptor Type F, Protein tyrosine phosphatase receptor type F polypeptide, Ptprf, PTPRF protein, PTPRF_HUMAN, Receptor linked protein tyrosine phosphatase LAR, Receptor type tyrosine protein phosphatase F, Receptor type tyrosine protein phosphatase F precursor, Receptor-type tyrosine-protein phosphatase F.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human PTPRF

Dilution: Flow-Cyt=1ug/Test

Purification: affinity purified by Protein A

Specificity: LAR Polyclonal Antibody detects endogenous levels of LAR protein.

Molecular Weight: 210 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P10586

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only