LARG rabbit pAb - ES5333

LARG rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5333-50, ES5333-100

Citations, Manuals and MSDS Available upon request.

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

Alternate Name: ARHGEF12; KIAA0382; LARG; Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 173kD

Human Gene ID: 23365

Human SWISS Prot NO: Q9NZN5

Subcellular Location: Cytoplasm. Membrane. Translocated to the membrane upon stimulation.

Research Use Only