Product Description

LATH Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60520-50, BS60520-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The PLUNC family of proteins are encoded by genes which map to chromosome 20 and are thought to play a potential role in the innate immune response in regions of the mouth, nose and lungs. As a member of the PLUNC family, BASE (breast cancer and salivary gland-expressed protein) is a 179 amino acid secreted protein that is named for its expression pattern. Due to its 63% sequence similarity with the related protein, Latherin, it is suggested that BASE is the major protein in sweat secretions and has important surfactant properties that lower surface tension. The expression pattern of BASE in many breast cancer cell lines suggests that it may be an easily accessible diagnostic breast cancer marker. Due to the fact that the gene encoding BASE is highly estrogen-repressed, expression of the gene is most likely dependent on HNF-3α and estrogen-mediated repression requiring ERα.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Putative BPIFA4P protein, BPI fold containing family A, member 4, pseudogene, Breast cancer and salivary gland-expressed protein, Putative latherin, BPIFA4P, BASE, LATH

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human LATH

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: LATH polyclonal antibody detects endogenous levels of LATH protein.

Molecular Weight: ~ 19 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q86YQ2

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only