Product Description

Latrophilin-1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26820-50, RA26820-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: adhesion G protein-coupled receptor L1 (ADGRL1) Homo sapiens This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IF/ICC, ELISA

Alternate Names: LPHN1, KIAA0821, LEC2, Latrophilin-1, Calcium-independent alpha-latrotoxin receptor 1, CIRL-1, Lectomedin-2

Clonality: Polyclonal

Dilution: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Storage: -20°C/1 year

Human Gene ID: 22859

Human SwissProt Number: O94910

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only