Product Description

LAX1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33052-50, RA33052-100

Citations, Manuals and MSDS Available upon request.

Background: function:Negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells and BCR (B-cell antigen receptor) -mediated signaling in B-cells.,induction:Up-regulated in T-cells following TCR engagement.,PTM:Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit:When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity:Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines.,

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 54900

Protein MW (KDa): 43

SWISS: Q8IWV1

Source: Rabbit

Research Use Only