LC3 A/B Rabbit Polyclonal Antibody - RA26827

LC3 A/B Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26827-50, RA26827-100

Citations, Manuals and MSDS Available upon request.

Background: function:Probably involved in formation of autophagosomal vacuoles (autophagosomes) .,PTM:The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.,similarity:Belongs to the MAP1 LC3 family.,subcellular location:LC3-II binds to the autophagic membranes.,subunit:3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins.,tissue specificity:Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB: 1:1000-2000

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

Protein MW (KDa): 14,16

SWISS: Q9H492/Q9GZQ8

Source: Rabbit

Research Use Only