Product Description

LC3 A/B Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26828-50, RA26828-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Probably involved in formation of autophagosomal vacuoles (autophagosomes)., PTM:The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II., similarity:Belongs to the MAP1 LC3 family., subcellular location:LC3-II binds to the autophagic membranes., subunit:3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins., tissue specificity:Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.,

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IF/ICC

Clonality: Polyclonal

Dilution: WB: 1:1000-2000 IF 1:100-300

Molecular Weight: 14, 16

Protein Molecular Weight (kDa): 14, 16

Storage: -20°C/1 year

Human SwissProt Number: Q9H492/Q9GZQ8

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only