LC3A/LC3B Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A5618-20, A5618-100
Citations, Manuals and SDS Available upon request.
Background: MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.
Synonyms: MAP1LC3B; ATG8F; LC3B; MAP1A/1BLC3; MAP1LC3B-a; MAP1LC3A; ATG8E; LC3; LC3A; MAP1ALC3; MAP1BLC3; LC3A/LC3B
GeneID: 84557/81631
Swiss-Prot: Q9GZQ8/Q9H492
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 14kDa
Observed Molecular Weight: 14kDa/16kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-60 of human LC3A (NP_115903.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Cancer, Signal Transduction, Cell Biology & Developmental Biology, Autophagy, Cytoskeleton, Microtubules, Endocrine & Metabolism, Mitochondrial metabolism, Cardiovascular, Heart, ATGs
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: 293T+Chloroquine, C6+Chloroquine
Cellular Location: Cytoplasm, Cytoplasmic Vesicle, EndoMembrane System, Lipid-anchor, Autophagosome, Autophagosome Membrane, Cytoskeleton
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.