Product Description

LDHA Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS6179-50, BS6179-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The lactate dehydrogenase family (LDH) catalyzes the final step of anaerobic glycolysis, the conversion of L-lactate and NAD to pyruvate and NADH. The LDH family consists of three members, LDH-A, LDH-B, and LDH-C, all of which form tetramers consisting four subunits. However, each family member displays a specific tissue distribution pattern with LDH-A and LDH-B predominant in several tissues, specifically LDH-A in muscle and LDH-B in heart, while LDH-C expression is confined to the testis and sperm. LDHs function as powerfμl markers for germ cell tumors. The genes encoding human LDH-A and LDH-C map to chromosome 11, while the human LDH-B gene maps to chromosome 12. Deficiency in the LDH-A gene is linked to exertional myoglobinuria.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF/ICC

Alternate Names: Cell proliferation-inducing gene 19 protein, GSD11, L lactate dehydrogenase A chain, L-lactate dehydrogenase A chain, l7R2, Lactate dehydrogenase 1, A chain, Lactate dehydrogenase A, Lactate dehydrogenase A4, Lactate dehydrogenase M, LDH A, LDH M, LDH muscle subunit, LDH muscle subunit, M LDH, LDH-A, LDH-M, LDH1, ldha, LDHA, LDHM, OTTMUSP00000017774, PIG19, Proliferation-inducing gene 19, Renal carcinoma antigen NY-REN-59,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Recombinant fμll length protein of human LDHA.

Dilution: WB, 1:500 - 1:2000 IHC, 1:10 - 1:100 IF/ICC, 1:10 - 1:100

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: LDHA polyclonal antibody detects endogenous levels of LDHA protein.

Molecular Weight: ~ 37 kDa

Pathway: Warburg Effect, Glutamine Metabolism, AMPK Signaling Pathway,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P00338

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only