LDHA Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90792-50, BS90792-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P00338
Host: Rabbit
Reactivity: Human, Mouse, rat
Applications: WB, IHC FC
All Applications: WB:1:500
IHC:1:200
FC:1:100-1:200
Background: Lactate dehydrogenase (LDH) is an enzyme present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. In medicine, LDH is often used as a marker of tissue breakdown as LDH is abundant in red blood cells and can function as a marker for hemolysis. In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C. Lactate dehydrogenase B (LDH-B, heart subunit, LDH-H) is involved in the conversion of L-lactate and NAD to pryruvate and NADH and it is predominantly localized in the heart tissue. Similar to other LDH subunit, LDH-B is considered to be an important marker for germ cell tumor.
Purification and Purity: Peptide affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: LDHA polyclonal antibody detects endogenous levels of LDHA protein.
Bioworld Molecular Weight: 37 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of LDHA on different cell lysates using anti-LDHA antibody at 1/500 dilution.
Positive control:
Lane 1: A549
Lane 2: Hela
Lane 3: A431
Lane 4: 293
Lane 5: Jurkat
Lane 6: MCF-7
Lane 7: Human liver
Lane 8: Human kidney
Lane 9: Human brain
Lane 10: Human thymus, Immunohistochemical analysis of paraffin-embedded rat liver tissue using anti-LDHA antibody. Counter stained with hematoxylin.
Alternative Name: LDH-A, LDH-M, Cell proliferation-inducing gene 19 protein, GSD11, L lactate dehydrogenase A chain, L-lactate dehydrogenase A chain, l7R2, Lactate dehydrogenase 1, A chain, Lactate dehydrogenase A, Lactate dehydrogenase A4, Lactate dehydrogenase M, LDH A, LDH M, LDH muscle subunit, LDH muscle subunit; M LDH, LDH-A, LDH-M, LDH1, ldha, LDHA, LDHM, OTTMUSP00000017774, PIG19, Proliferation-inducing gene 19, Renal carcinoma antigen NY-REN-59,
Immunogen: peptide
Conjugate: Unconjugated
Modification: Unmodified