LDHB Polyclonal Antibody - BT-AP10872

LDHB Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP10872-20, BT-AP10872-50, BT-AP10872-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

Research Areas: Cancer; Metabolism; Signal transduction; Cell biology

Target Protein: LDHB

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: L-lactate dehydrogenase B chain

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P07195; Mouse: P16125; Rat: P42123

Synonyms: L-lactate dehydrogenase B chain;LDH-B;EC 1.1.1.27;LDH heart subunit;LDH-H;Renal carcinoma antigen NY-REN-46

GeneID: Human: 3945

Research Use Only