Product Description

LDLR Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33068-50, RA33068-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: low density lipoprotein receptor (LDLR) Homo sapiens The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 94

Protein Molecular Weight (kDa): 94

Storage: -20°C/1 year

Human Gene ID: 3949

Human SwissProt Number: P01130

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only