Product Description

LECT1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8321-50, BS8321-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodμlin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascμlar zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascμlar invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascμlarized and replaced by bone. It may be involved also in the broad control of tissue vascμlarization during development. Alternative splicing resμlts in mμltiple transcript variants encoding different isoforms.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IF/ICC

Alternate Names: CNMD, BRICD3, CHM-I, CHM1, LECT1, MYETS1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human LECT1(NP_008946.1).

Dilution: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:100

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 37kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O75829

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only