LECT1 rabbit pAb - ES11364

LECT1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11364-50, ES11364-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularizat

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Rat; Mouse

Immunogen: Synthesized peptide derived from human protein . at AA range: 150-230

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 36kD

Human Gene ID: 11061

Human SWISS Prot NO: O75829

Subcellular Location: [Chondromodulin-1]: Secreted, extracellular space, extracellular matrix. Accumulated in the inter-territorial matrix of cartilage.; [Chondrosurfactant protein]: Endomembrane system; Single-pass membrane protein.

Research Use Only