Lefty rabbit pAb - ES4374

Lefty rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4374-50, ES4374-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Aug 2016],

Alternate Name: LEFTY1; LEFTB; LEFTYB; Left-right determination factor 1; Left-right determination factor B; Protein lefty-1; Protein lefty-B; LEFTY2; EBAF; LEFTA; LEFTYA; TGFB4; PSEC0024; Left-right determination factor 2; Endometrial bleeding-associated factor; Left-right determination factor A; Protein lefty-2; Protein lefty-A; Transforming growth factor beta-4; TGF-beta-4

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human LEFTY1/LEFTY2. AA range:301-350

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 40kD

Human Gene ID: 10637/7044

Human SWISS Prot NO: O75610/O00292

Subcellular Location: Secreted

Research Use Only