Product Description

Leptin (5C11) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3076-50, MB3076-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P41159

Host: Mouse

Reactivity: Human

Applications: ELISA

All Applications: ELISA: 1/10000

Background: This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Indirect ELISA assay for antiLeptin mouse mAb. Antigen coating concentration: 4ug/ml.

Specificity: IgG2a

Alternative Name: OB; OBS; LEPD; LEP

Immunogen: Purified recombinant full length of human Leptin protein expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified