Product Description

lgA Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66771-50, MB66771-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Immunoglobμlins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disμlfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobμlin A (IgA) is the main protein of the mucosal immune system. It is generated by B cells in gut-associated lymphoid tissues. Daily production of IgA exceeds that of any of the other immunoglobμlins. The IgA heavy chain is an a-chain, and the light chains are either k- or l- chains. IgA exists mainly in dimers but can also exist as polymers or as monomers. Dimers and polymers contain a joining (J) chain that can be bound by the polymeric immunoglobμlin receptor (pIgR) for transportation of the molecμle to mucosal surfaces.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: Ig alpha-1 chain C region

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human lgA. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Specificity: Recognizes endogenous levels of lgA protein.

Molecular Weight: ~ 55 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P01876

Product: Mouse IgM. Supplied in crude ascites with 0.01% sodium azide.

Research Use Only