Product Description

LGR5/GPR49 Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40123-50, BS40123-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellμlar Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.

Category: Primary Antibody

Reactivity: Human Mouse Rat

Host: Rabbit

Applications: WB, IP, FC

Alternate Names: FEX, GPR49, GPR67, GRP49, LGR5, HG38, 8

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: A synthesized peptide derived from human LGR5/GPR49

Dilution: WB 1:500~1:2000 IP 1:50 FC 1:200

Purification: Affinity-chromatography

Specificity: LGR5/GPR49 Antibody detects endogenous levels of total LGR5/GPR49

Molecular Weight: 100kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O75473

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only