LGR5 Polyclonal Antibody - BT-AP10893

LGR5 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP10893-20, BT-AP10893-50, BT-AP10893-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cancer; Signal transduction; Stem cells

Target Protein: LGR5

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Leucine-rich repeat-containing G-protein coupled receptor 5

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O75473; Mouse: Q9Z1P4

Synonyms: Leucine-rich repeat-containing G-protein coupled receptor 5;G-protein coupled receptor 49;G-protein coupled receptor 67;G-protein coupled receptor HG38

GeneID: Human: 8549

Research Use Only