Product Description

LIF Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60463-50, BS60463-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Embryonic stem (ES) cells are the focus of much research and represent great therapeutic potential as they can be propagated indefinitely in an undifferentiated state while possessing the ability to differentiate into all embryonic germ layers (endoderm, ectoderm and mesoderm) both in vivo and in vitro. LIF (leukemia inhibitory factor), also known as MLPLI (melanoma-derived LPL inhibitor), HILDA, DIA or CDF, is a 202 amino acid secreted protein and lymphoid factor that participates in the maintenance of ES cell pluripotency by suppressing spontaneous ES cell differentiation. Secreted LIF precursor is further processed into a biologically active glycoprotein. Expressed by a wide variety of cells including activated T lymphocytes, monocytes, mast cells and neuronal cells, LIF is suggested to promote survival and growth of axons in vitro and is involved in immune tolerance at the maternal-fetal interface. LIF may also participate in fat and bone metabolism and regμlate epithelial conversion during kidney development.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Leukemia inhibitory factor, LIF, Differentiation-stimμlating factor, D factor, Melanoma-derived LPL inhibitor, MLPLI, INN=Emfilermin, LIF, HILDA

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human LIF.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: LIF polyclonal antibody detects endogenous levels of LIF protein.

Molecular Weight: ~ 22 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P15018

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only