Product Description

LIFR Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26861-50, RA26861-100

Citations, Manuals and MSDS Available upon request.

Background: leukemia inhibitory factor receptor alpha (LIFR) Homo sapiens This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t (5;8) (p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: LIFR; Leukemia inhibitory factor receptor; LIF receptor; LIF-R; CD118

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 3977

Protein MW (KDa): 120

SWISS: P42702

Source: Rabbit

Research Use Only