LIGHT Polyclonal Antibody - RA26862

LIGHT Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26862-50, RA26862-100

Citations, Manuals and MSDS Available upon request.

Background: tumor necrosis factor superfamily member 14 (TNFSF14) Homo sapiens The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM) . This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: TNFSF14; HVEML; LIGHT; Tumor necrosis factor ligand superfamily member 14; Herpes virus entry mediator ligand; HVEM-L; Herpesvirus entry mediator ligand; CD antigen CD258

Applications: IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 8740

SWISS: O43557

Source: Rabbit

Research Use Only