Product Description

LIGO1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33082-50, RA33082-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination., PTM:N-glycosylated. Contains predominantly high-mannose glycans., similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain., similarity:Contains 13 LRR (leucine-rich) repeats., subunit:Homotetramer. Forms ternary complex with RTN4R/NGFR and RTN4R/TNFRSF19., tissue specificity:Expressed exclusively in the central nervous system. Highest level in the in amygdala, hippocampus, thalamus and cerebral cortex. In the rest of the brain a basal expression seems to be always present. Up-regulated in substantia nigra neurons from Parkinson disease patients.,

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 68

Protein Molecular Weight (kDa): 68

Storage: -20°C/1 year

Human Gene ID: 84894

Human SwissProt Number: Q96FE5

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only