LILRB2/CD85d/ILT4 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A12157-20, A12157-100
Citations, Manuals and SDS Available upon request.
Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: ILT4; LIR2; CD85D; ILT-4; LIR-2; MIR10; MIR-10; LILRB2/CD85d/ILT4
GeneID: 10288
Swiss Prot: Q8N423
Tested Applications: ELISA, WB
Reactivity: Human
Calculated Molecular Weight: 65kDa
Observed Molecular Weight: 65kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 479-598 of human LILRB2/CD85d/ILT4 (NP_005865.3).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Immunology Inflammation, CDs
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: THP-1, U-87MG
Cellular Location: Membrane, Single-pass Type I Membrane Protein,
Keywords: 10288, sc-33454, sc-33455, sc-33456, LILRB2, CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-10, MIR10, leukocyte immunoglobulin like receptor B2, leukocyte immunoglobulin-like receptor subfamily B member 2, CD85 antigen-like family member D, Ig-like transcript 4, leucocyte Ig-like receptor B2, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2, monocyte/macrophage immunoglobulin-like receptor 10, myeloid inhibitory receptor 10, Q8N423, Leukocyte Immunoglobulin Like Receptor B2, Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM And ITIM Domains), Member 2, Monocyte/Macrophage Immunoglobulin-Like Receptor 10, CD85 Antigen-Like Family Member D, Myeloid Inhibitory Receptor 10, Leucocyte Ig-Like Receptor B2, Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2, Leukocyte Immunoglobulin-Like Receptor 2, Immunoglobulin-Like Transcript 4, Ig-Like Transcript 4, CD85d Antigen, ILT 4, LIR 2, MIR 10, sc33454, sc 33454, sc33455, sc 33455, sc33456, sc 33456, LILRB2/CD85d/ILT4
Symbol: LILRB2
Category: Polyclonal Antibodies
Research Use Only