LILRB5 Polyclonal Antibody
Catalogue Numbers: BS61498-50, BS61498-100
Sizes: 50µl, 100µl
Alternative Name: Leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; LIR-8; CD85c; CD85c; LIR8
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: O75023
Host: Rabbit
Reactivity: Human, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: This gene is a member of the leukocyte immunoglobulin-likereceptor (LIR) family, which is found in a gene cluster atchromosomal region 19q13.4. The encoded protein belongs to thesubfamily B class of LIR receptors which contain two or fourextracellular immunoglobulin domains, a transmembrane domain, andtwo to four cytoplasmic immunoreceptor tyrosine-based inhibitorymotifs (ITIMs). Several other LIR subfamily B receptors areexpressed on immune cells where they bind to MHC class I moleculeson antigen-presenting cells and inhibit stimulation of an immuneresponse. Multiple transcript variants encoding different isoformshave been found for this gene.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: LILRB5 polyclonal antibody detects endogenous levels of LILRB5 protein.
Bioworld Molecular Weight: ~ 64 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of LILRB5 polyclonal antibody at 1:500 dilution
Lane 1: MCF-7 whole cell lysate(20ug)
Lane 2: THP-1 whole cell lysate(40ug)
Immunogen: A synthetic peptide corresponding to amino acids 128-173 of Human LILRB5.
Conjugate: Unconjugated
Modification: Unmodified