Product Description

LIN-28 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA11620-50, RA11620-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: lin-28 homolog A (LIN28A) Homo sapiens This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015],

Reactivity: Human

Host: Mouse

Applications: WB, IF/ICC, ELISA

Alternate Names: LIN28A, CSDD1, LIN28, ZCCHC1, Protein lin-28 homolog A, Lin-28A, Zinc finger CCHC domain-containing protein 1

Clonality: Monoclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Storage: -20°C/1 year

Condition: Antibody are purified by protein G affinity chromatography. Liquid in 0.01M Phosphate buffer, pH 7.4 containing 0.03% sodium azide.

Human Gene ID: 79727

Research Use Only