Lin28 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90798-50, BS90798-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9H9Z2(Human)
Host: Rabbit
Reactivity: Human
Applications: WB, IP, , FC
All Applications: WB:1:500-1:1,000
IP:1:10-1:50
FC:1:50-1:100
Background: LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein sysnthesis efficiency and binds to the growth and differentiation factor IGF-II.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Lin28 polyclonal antibody detects endogenous levels of Lin28 protein.
Bioworld Molecular Weight: 23 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Lin-28 on NCCIT cells lysates using anti-Lin-28 antibody at 1/500 dilution., Flow cytometric analysis of Hela cells with Lin-28 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
Alternative Name: Lin-28A, LIN28A, AL024421, CSDD1, CSDD2, FLJ12457, Lin 28, Lin 28 homolog (C. elegans), Lin 28 homolog A (C. elegans), Lin 28 homolog A, Lin 28 homolog, Lin-28A, Lin28, Lin28, C. elegans, homolog of, A, LIN28A, LN28A, Protein lin-28 homolog A, Protein lin-28 homolog B, RNA binding protein lin 28, Tex17, ZCCHC1, Zinc finger CCHC domain containing 1, Zinc finger CCHC domain containing protein 1, Zinc finger CCHC domain-containing protein 1,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified