Product Description

LIN28A (9G2) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3144-50, MB3144-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q9H9Z2

Host: Mouse

Reactivity: Human

Applications: WB, ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: Involved in the timing of developmental events and choice of stage specific cell fates. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 23 kDa; Observed MW: 23 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunofluorescence analysis of LIN28A in Hela cells were transfected with pMX construct of Human LIN28 using LIN28A antibody, Immunofluorescence analysis of LIN28A in NTERA-2 cells using LIN28A antibody. Blue: DRAQ5 fluorescent DNA dye., Western blot analysis of LIN28A in NTERA-2 lysates using LIN28A antibody.

Alternative Name: CSDD1; FLJ12457; LIN 28; Lin-28A; LIN28; LIN28A; LN28A_HUMAN; Protein lin-28 homolog A; ZCCHC1; Zinc finger CCHC domain-containing protein 1.

Immunogen: Purified recombinant fragment of LIN28 (aa93-209) expressed in E. Coli.

Conjugate: Unconjugated

Modification: Unmodified