Product Description

LIN28A Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB0149-50, MB0149-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9H9Z2

Host: Mouse

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1:1000

Background: LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein synthesis efficiency and binds to the growth and differentiation factor IGF-II.

Purification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of LIN28A and does not cross-react with related proteins

Bioworld Molecular Weight: Predicted band size:26KDa
Observed band size:26KDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western BlotDetection of LIN28 in NTERA & F9 cell lysates using LIN28 antibody (1:1000 diluted).

Alternative Name: Protein lin-28 homolog A; Lin-28A; Zinc finger CCHC domain-containing protein 1; LIN28A; CSDD1; LIN28; ZCCHC1

Immunogen: Recombinant full length Human LIN28A.

Conjugate: Unconjugated

Modification: Unmodified