Product Description

lipin1 Phospho-ser889 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36907-50, RA36907-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: lipin 1 (LPIN1) Homo sapiens This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Phosphatidate phosphatase LPIN1 (EC 3.1.3.4) (Lipin-1)

Clonality: Polyclonal

Dilution: WB 1:500-2000

Storage: -20°C/1 year

Human Gene ID: 23175

Human SwissProt Number: Q14693

Condition: Liquid in PBS containing 50% glycerol, and 0.223% sodium azide.

Research Use Only