LITAF Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA33092-50, RA33092-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: lipopolysaccharide induced TNF factor (LITAF) Homo sapiens Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2014], Reactivity: Human, Rat, Mouse Host: Rabbit Applications: WB, ELISA Clonality: Polyclonal Dilution: WB 1:500-2000 ELISA 1:5000-20000 Molecular Weight: 17 Protein Molecular Weight (kDa): 17 Storage: -20°C/1 year Human Gene ID: 9516 Human SwissProt Number: Q99732 Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Research Use Only