LMNB2 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90803-50, BS90803-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q03252
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, ICC IHC
All Applications: WB:1:1,000-1:2,000
ICC:1:200
IHC:1:200
Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Defects in LMNB2 are a cause of partial acquired lipodystrophy (APLD), which is a rare childhood disease characterized by loss of subcutaneous fat from the face and trunk.
Purification and Purity: Peptide affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: LMNB2 polyclonal antibody detects endogenous levels of LMNB2 protein.
Bioworld Molecular Weight: 68 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Lamin B2 on different cell lysates using anti-LMNB2 antibody at 1/1000 dilution.
Positive control:
Lane 1: Hela
Lane2:Jurkat
Lane 3: HepG2
Lane 4:Raji, ICC staining of LMNB2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: LMNB2, LAMB 2, LAMB2, Lamin-B2, LMN 2, LMN B2, LMN2, LMNB 2, LMNB2, LMNB2, MGC2721, RGD1563803,
Immunogen: peptide
Conjugate: Unconjugated
Modification: Unmodified