LMTK3 Polyclonal Antibody - BT-AP05045

LMTK3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05045-20, BT-AP05045-50, BT-AP05045-100

Citations, Manuals and MSDS Available upon request.

Background: LMTK3 (Lemur Tyrosine Kinase 3) is a Protein Coding gene. Among its related pathways are ERK Signaling and Akt Signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AATK. rotein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed: 21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).

Research Areas: Others

Target Protein: LMTK3

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: LMTK3 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 153661

UniProt Accession: Human: Q96Q04; Mouse: Q5XJV6

Synonyms: LMTK3; KIAA1883; TYKLM3; Serine/threonine-protein kinase LMTK3; Lemur tyrosine kinase 3

GeneID: Human: 114783; Mouse: 381983

Research Use Only