LN28B Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA33099-50, RA33099-100 Citations, Manuals and MSDS Available upon request. Background: lin-28 homolog B (LIN28B) Homo sapiens The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012], Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000 Applications: WB; ELISA Species Cross-Reactivity: Human; Mouse GeneID (Human): 389421 Protein MW (KDa): 27 SWISS: Q6ZN17 Source: Rabbit Research Use Only