LN28B Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA33099-50, RA33099-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: lin-28 homolog B (LIN28B) Homo sapiens The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012], Reactivity: Human, Mouse Host: Rabbit Applications: WB, ELISA Clonality: Polyclonal Dilution: WB 1:500-2000 ELISA 1:5000-20000 Molecular Weight: 27 Protein Molecular Weight (kDa): 27 Storage: -20°C/1 year Human Gene ID: 389421 Human SwissProt Number: Q6ZN17 Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Research Use Only