LPHN1 Polyclonal Antibody Sizes: 50μl, 100μl Catalogue Numbers: BS65810-50, BS65810-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resμlted in two subunits (a large extracellμlar N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing resμlts in mμltiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008] Category: Primary Antibody Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit Host: Rabbit Applications: IHC-P Alternate Names: Calcium independent alpha latrotoxin receptor 1, Calcium-independent alpha-latrotoxin receptor 1, CIRL-1, CIRL1, CL1, CLIBA, G protein-coupled receptor for alpha-Latrotoxin, KIAA0821, Latrophilin 1, Latrophilin-1, Latrophilin1, LEC2, Lectomedin 2, Lectomedin-2, LPHN 1, LPHN1, LPHN1_HUMAN. Clonality: Polyclonal Conjugate: Unconjugated Modification: Unmodification Immunogen: KLH conjugated synthetic peptide derived from human LPHN1:201-300/1474 Dilution: IHC-P=1:100-500 Purification: affinity purified by Protein A Specificity: LPHN1 Polyclonal Antibody detects endogenous levels of LPHN1 protein. Molecular Weight: ~160 kDa Storage and Stability: Store at 4°C short term. Aliquot and store at -17°C long term. Avoid freeze-thaw cycles. SwissProt: O94910 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Research Use Only