LPIN1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-17873-60, E-AB-17873-120, E-AB-17873-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: LPIN1
Target Synonym: EC=3.1.3.4; KIAA0188 ; Lipin-1; Lpin1; LPIN1; PAP1; Phosphatidate phosphatase LPIN1
Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q14693
Background: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.
Concentration: 1.4 mg/mL
Immunogen: Synthetic peptide of human LPIN1
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Calculated MW: 99 kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only