LRAT rabbit pAb - ES2724

LRAT rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2724-50, ES2724-100

Citations, Manuals and MSDS Available upon request.

Background: lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) (LRAT) Homo sapiens The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014],

Alternate Name: LRAT; Lecithin retinol acyltransferase; Phosphatidylcholine--retinol O-acyltransferase

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human LRAT. AA range:111-160

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 27kD

Human Gene ID: 9227

Human SWISS Prot NO: O95237

Subcellular Location: Endoplasmic reticulum membrane; Single-pass membrane protein. Rough endoplasmic reticulum. Endosome, multivesicular body. Cytoplasm, perinuclear region. Present in the rough endoplasmic reticulum and multivesicular body in hepatic stellate cells. Present in the rough endoplasmic reticulum and perinuclear region in endothelial cells (By similarity).

Research Use Only