Product Description

LRBA Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33115-50, RA33115-100

Citations, Manuals and MSDS Available upon request.

Background: LPS responsive beige-like anchor protein (LRBA) Homo sapiens The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS) . The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p 1:50-300

Applications: IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 987

Protein MW (KDa): 314

SWISS: P50851

Source: Rabbit

Research Use Only