LRBA rabbit pAb - ES9768

LRBA rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES9768-50, ES9768-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],

Source: Rabbit

Applications: IHC; IF

Dilution: IHC-p 1:50-300

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human protein . at AA range: 1970-2050

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 314kD

Human Gene ID: 987

Human SWISS Prot NO: P50851

Subcellular Location: Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus trans-Golgi network membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein.

Research Use Only