LRIG1 rabbit pAb - ES11850

LRIG1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11850-50, ES11850-100

Citations, Manuals and MSDS Available upon request.

Background: domain:The LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding. This interaction is abolished only when these two domains are deleted., function:Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation., induction:By EGF., similarity:Contains 17 LRR (leucine-rich) repeats., similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains., subunit:Interacts with EGFR/ERBB1, ERBB2, ERBB3 and ERBB4., tissue specificity:Widely expressed.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 120kD

Human Gene ID: 26018

Human SWISS Prot NO: Q96JA1

Subcellular Location: Cell membrane; Single-pass type I membrane protein.

Research Use Only