Product Description

LRP2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33138-50, RA33138-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: LDL receptor related protein 2 (LRP2) Homo sapiens The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of th

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: IHC-p, IF (paraffin section)

Clonality: Polyclonal

Dilution: IHC-p 1:50-300

Molecular Weight: 512

Protein Molecular Weight (kDa): 512

Storage: -20°C/1 year

Human Gene ID: 4036

Human SwissProt Number: P98164

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only